Congress of neurological surgeons systematic review and evidence-based guidelines update on the role of cytoreductive surgery in the management of progressive glioblastoma in adults

Hayes H Patrick ¹, Jonathan H Sherman ², J Bradley Elder ³, Jeffrey J Olson ⁴Affiliations expand

• PMID: 35246769
• DOI: 10.1007/s11060-021-03881-w

Abstract

Question: In patients with previously diagnosed glioblastoma who are suspected of experiencing progression, does repeat cytoreductive surgery improve progression free survival or overall survival compared to alternative interventions?

Target population: These recommendations apply to adults with previously diagnosed glioblastoma who are suspected of experiencing progression of the neoplastic process and are amenable to surgical resection.

Recommendation: Level II: Repeat cytoreductive surgery is recommended in progressive glioblastoma patients to improve overall survival.

Keywords: Cytoreductive surgery; Glioblastoma; Recurrent.

© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

References

1. Archavlis E, Tselis N, Birn G, Ulrich P, Zamboglou N (2014) Salvage therapy for recurrent glioblastoma multiforme: a multimodal approach combining fluorescence-guided resurgery, interstitial irradiation, and chemotherapy. Neurol Res 36:1047–1055 – DOI

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