REVIEW – Cavernous sinus lesions

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The cavernous sinus is a complex structure susceptible to a wide variety of vascular, neoplastic and inflammatory pathologies. Vascular pathologies include ICA aneurysms, carotid-cavernous fistulas, cavernous sinus thrombosis, and cavernous hemangioma. Neoplasms that involve the cavernous sinus include pituitary adenoma, meningioma, schwannoma, lymphoma, perineural tumor spread, metastases, and direct tumor invasion. Infectious and inflammatory diseases include Tolosa-Hunt syndrome, sarcoidosis, granulomatosis with polyangiitis, IgG-4 related disease and invasive fungal infections.

Review Clin Imaging

  • 2020 Dec;68:71-89. doi: 10.1016/j.clinimag.2020.06.029. Epub 2020 Jun 18.

Cavernous sinus lesions

Kamran Munawar 1Gopi Nayak 1Girish M Fatterpekar 1Chandra Sen 2David Zagzag 3Elcin Zan 1Mari Hagiwara 4Affiliations expand

Abstract

The cavernous sinus is a complex structure susceptible to a wide variety of vascular, neoplastic and inflammatory pathologies. Vascular pathologies include ICA aneurysms, carotid-cavernous fistulas, cavernous sinus thrombosis, and cavernous hemangioma. Neoplasms that involve the cavernous sinus include pituitary adenoma, meningioma, schwannoma, lymphoma, perineural tumor spread, metastases, and direct tumor invasion. Infectious and inflammatory diseases include Tolosa-Hunt syndrome, sarcoidosis, granulomatosis with polyangiitis, IgG-4 related disease and invasive fungal infections. In this article, we review the clinical and imaging findings of a number of pathologies involving the cavernous sinus, focusing on key features that can narrow the differential diagnosis and, in some cases, support a particular diagnosis.

Keywords: Carotid-cavernous fistula; Cavernous sinus; Head and neck; Meningioma; Neuroradiology; Tolosa-Hunt syndrome.

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