Trigeminal neuralgia (TN) is a disease of unclear pathogenesis. It has a low incidence and is not fatal, but it can cause afflicted patients’ depression or suicide. In the past, neurovascular compression was considered to be the main cause of TN, but recent studies have found that neurovascular contact is also common in asymptomatic patients and the asymptomatic side in symptomatic patients.
Recent Advances of Magnetic Resonance Neuroimaging in Trigeminal Neuralgia
Chen Zeng 1, Chuan Zhang 1, Ye-Han Li 1, Xu Feng 1, Man-Jing Zhang 1, Ru-Hui Xiao 1, Han-Feng Yang 2Affiliations expand
- PMID: 33821366
- DOI: 10.1007/s11916-021-00957-0
Abstract
Trigeminal neuralgia (TN) is a disease of unclear pathogenesis. It has a low incidence and is not fatal, but it can cause afflicted patients’ depression or suicide. In the past, neurovascular compression was considered to be the main cause of TN, but recent studies have found that neurovascular contact is also common in asymptomatic patients and the asymptomatic side in symptomatic patients. This indicates that the neurovascular contact is not, or is only to a lesser extent, a factor in the development of TN. Thus, the study of the peripheral branches of the trigeminal nerve is necessary to understand the etiology of TN. With the development of imaging technology and the emergence of various imaging modalities, it is possible to study the etiology of TN and the pathological changes of related structures by magnetic resonance neuroimaging. This article reviews the recent advances in magnetic resonance neuroimaging of the trigeminal nerve.
Keywords: MRI; Peripheral branches; Trigeminal nerve; Trigeminal neuralgia.
Similar articles
- Trigeminal neuralgia: differences in magnetic resonance imaging characteristics of neurovascular compression between symptomatic and asymptomatic nerves.Suzuki M, Yoshino N, Shimada M, Tetsumura A, Matsumura T, Fukayama H, Kurabayashi T.Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 Jan;119(1):113-8. doi: 10.1016/j.oooo.2014.09.013. Epub 2014 Sep 16.PMID: 25442253
- Trigeminal neurovascular contact in SUNCT and SUNA: a cross-sectional magnetic resonance study.Lambru G, Rantell K, O’Connor E, Levy A, Davagnanam I, Zrinzo L, Matharu M.Brain. 2020 Dec 1;143(12):3619-3628. doi: 10.1093/brain/awaa331.PMID: 33301567 Free PMC article.
- Structural Magnetic Resonance Imaging Can Identify Trigeminal System Abnormalities in Classical Trigeminal Neuralgia.DeSouza DD, Hodaie M, Davis KD.Front Neuroanat. 2016 Oct 19;10:95. doi: 10.3389/fnana.2016.00095. eCollection 2016.PMID: 27807409 Free PMC article. Review.
- Atrophic changes in the trigeminal nerves of patients with trigeminal neuralgia due to neurovascular compression and their association with the severity of compression and clinical outcomes.Leal PR, Barbier C, Hermier M, Souza MA, Cristino-Filho G, Sindou M.J Neurosurg. 2014 Jun;120(6):1484-95. doi: 10.3171/2014.2.JNS131288. Epub 2014 Apr 18.PMID: 24745706
- Practice parameter: the diagnostic evaluation and treatment of trigeminal neuralgia (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the European Federation of Neurological Societies.Gronseth G, Cruccu G, Alksne J, Argoff C, Brainin M, Burchiel K, Nurmikko T, Zakrzewska JM.Neurology. 2008 Oct 7;71(15):1183-90. doi: 10.1212/01.wnl.0000326598.83183.04. Epub 2008 Aug 20.PMID: 18716236 Review.
References
- Cruccu G, Finnerup NB, Jensen TS, Scholz J, Sindou M, Svensson P, et al. Trigeminal neuralgia: new classification and diagnostic grading for practice and research. Neurology. 2016;87(2):220–8.