NEJM series on Stroke – Patent Foramen Ovale: close, or not to close?

This is a comeback for PFO closure!

This series comprised of 3 trial published in the New England Journal of Medicine that enrolled patients after stroke with PFO and either left-to-right shunt or atrial aneurysms. All 3 clinical trials showed the benefit of PFO closure on this patient population in comparison with antiplatelet therapy or anticoagulation.

Enjoy the read at NEJM:


Current Internal Medicine resident at Boston University Medical Center, future Hematology and Oncology fellow at Beth Israel Deaconess Medical Center, Harvard Medical School.

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