STEROIDS (Guidelines TBI 2016, 4th Ed.)
LEVEL I
The use of steroids is not recommended for improving outcome or reducing ICP. In patients with severe TBI, high-dose methylprednisolone was associated with increased mortality and is contraindicated.
CHANGES FROM PRIOR EDITION
The body of evidence was updated to include the 6-month outcomes of the CRASH trial. There were no changes to the recommendations for this topic.
READ MORE: https://braintrauma.org/guidelines/guidelines-for-the-management-of-severe-tbi-4th-ed#/
