Surgical Results of Large and Giant Pituitary Adenomas with Special Consideration of Ophthalmologic

Publication year: 2011
Source: World Neurosurgery, Volume 76, Issues 1-2, July-August 2011, Pages 141-148
Ahmet Murat, Müslüman , Tufan, Cansever , Adem, Yılmaz , Ayhan, Kanat , Ersin, Oba , …
Objective: To analyze functioning and nonfunctioning pituitary adenomas (PAs) >3 cm, with special emphasis on preoperative and postoperative visual functions. Methods: The cases consisted of 49 women and 54 men with mean age of 43.2 years (range 19–66 years). All cases had a macroadenoma >3 cm in diameter. The transsphenoidal approach was performed in 117 procedures, and the transcranial approach was performed in 8 procedures. Radical tumor excision was achieved in 50 of 103 patients. Postoperative evaluation was done in 88 patients. Preoperative and postoperative visual acuity, visual field, and ocular fundi and their relationship with the pattern and duration of the symptoms…


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