The role of depression in cancer is still relatively poorly studied because cancer patients are often excluded from clinical trials examining depression treatment. Depression and Cancer is the third book in a series by the World Psychiatric Association linking depression with various physical diseases. This is a timely and important topic for oncologists generally and radiation oncologists specifically. This book, written by leaders in the field of psychooncology, does an excellent job of defining the problem and offers a series of chapters on approaches to treatment. It consists of nine chapters dealing with etiology, diagnosis, biology, and treatment.