Radiation-induced moyamoya disease after childhood astrocytoma

Publication year: 2011
Source: Journal of Clinical Neuroscience, In Press, Corrected Proof, Available online 23 July 2011
Ben, Manion , Wen-Shan, Sung
Adjunctive radiation treatment of childhood intracranial neoplasms of grade II or higher creates a risk of subsequent vasculopathy. A 28-year-old male presented with a Glasgow Coma Scale 12 after acute collapse and hemiparesis with an intraparenchymal haematoma. Emergent craniotomy, histopathology and subsequent imaging confirmed the cause as radiation-induced moyamoya disease, subsequent to treatment for a grade 2 astrocytoma 24years previously. He had been lost to follow-up after normal serial imaging performed up to 10years after his initial diagnosis. Long term surveillance imaging may be of benefit in identifying treatable vascular anomalies.

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