The clinico-radiological spectrum of isolated cortical vein thrombosis

Publication year: 2011
Source: Journal of Clinical Neuroscience, In Press, Corrected Proof, Available online 20 July 2011
Rahul, Rathakrishnan , Vijay K., Sharma , Teoh Hock, Luen , Bernard P.L., Chan
Isolated cortical vein thrombosis (ICVT) in the absence of sinus or great venous involvement is rare. Various MRI sequences have been proposed for diagnostic accuracy, although follow-up data are limited. The optimal management strategy remains uncertain. Patients with ICVT treated between 2006 and 2008 were retrospectively studied. Diagnostic and follow-up neuroimaging were reviewed independently, and we evaluated their treatment and outcomes. Five patients (mean age 41years; range, 25–54years) were included. All presented with seizures. Focal neurological deficits were noted in one patient only. T2∗ susceptibility-weighted MRI abnormalities were observed in all patients. T2-weighted parenchymal hyperintensities involving the cortical–subcortical regions around…


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