Comment Combining statins with interferon beta in multiple sclerosis: think twice, it might not be all right

[Comment] Combining statins with interferon beta in multiple sclerosis: think twice, it might not be all right

Since the finding that cholesterol-lowering statins could induce T-cell-mediated immune modulation and reverse paralysis in mice with experimental autoimmune encephalomyelitis (EAE), there has been substantial interest in whether this class of drugs is beneficial in multiple sclerosis. One question that has not been answered is whether a statin used alone is beneficial; more energy has been devoted to establishing whether statins can provide added benefit when combined with interferon beta, the most commonly prescribed class of drug in multiple sclerosis.

http://www.thelancet.com/journals/laneur/article/PIIS1474-4422(11)70153-3/fulltext?rss=yes

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