Clinical characteristics and diagnostic imaging of epidermoid tumors
Publication year: 2011 Source: Journal of Clinical Neuroscience, In Press, Corrected Proof, Available online 13 July 2011Daniel, Nagasawa , Andrew, Yew , Michael, Safaee , Brendan, Fong , Quinton, Gopen , …Epidermoid tumors are rare, benign congenital lesions which typically present between the third and fifth decades of life. They are thought to originate from ectodermal cells misplaced during neural tube formation and separation. While epidermoids may present anywhere in the cranial vault, they are characteristically located intradurally and in a paramedian position within the cerebellopontine angle and parasellar regions. Although imaging results may vary depending upon cystic content, CT scanning generally reveals a well-circumscribed, nonenhancing, lobulated, hypodense mass. They are hypointense on T1-weighted MRI, and hyperintense on T2-weighted MRI, diffusion-weighted imaging and fluid-attenuated inversion recovery sequences. The use of appropriate…