Natural history of spinal deformity in a patient with Ehlers-Danlos syndrome: case report with 20-year follow-up

Publication year: 2011
Source: The Spine Journal, In Press, Corrected Proof, Available online 2 June 2011
Deepa, Natarajan , Dino, Samartzis , Yat-Wa, Wong , Keith D.K., Luk , Kenneth M.C., Cheung
Background context: Scoliosis can present in patients with Ehlers-Danlos syndrome (EDS) and can be surgically treated despite possible complications. The long-term natural history of the progression of spinal deformity, particularly scoliosis, and associated complications in EDS patients remains relatively unknown. Purpose: To assess the progression of spinal deformity and associated complications in a patient with EDS, who was not surgically treated for her spine condition and was followed up for 20 years. Study design: A case report. Methods: A 9-year-old female with EDS presented to the orthopedic clinic with scoliosis and mild thoracic hyperkyphosis. The patient was followed up for a 20-year period. Progression of her spinal…