Trends in treatment and outcomes of pediatric craniopharyngioma, 1975-2011 BackgroundCraniopharyngioma tumors and their treatment can lead to significant long-term morbidity due to their proximity to vital structures. The optimal treatment has been debated for many years. We aimed to review the long-term outcomes of children treated for craniopharyngioma in our institution over the past decade [...]

Dura Splitting Decompression for Chiari I Malformation in Pediatric Patients: Clinical Outcomes, He BACKGROUND: Dural splitting decompression may be an effective and safe treatment for Chiari I malformation. OBJECTIVE: To compare clinical outcomes, complications, and resource utilization for patients undergoing Chiari I decompression with or without duraplasty. METHODS: Between 2000 and 2009, the senior author [...]

Surgical treatment of transsphenoidal encephaloceles: transpalatal versus combined transpalatal and Journal of Neurosurgery: Pediatrics, Volume 11, Issue 5, Page 505-510, May 2013. Object Transsphenoidal encephalocele (TSEC) is a rare developmental anomaly with herniation of neural elements including pituitary gland or optic apparatus, through a defect of sphenoid bone. To prevent obstructive dyspnea, endocrine dysfunction, or [...]

Abstract Objective. To assess the natural history of isolated syringomyelia in children. Methods. MRI reports from February 2007 to August 2011 mentioning syrinx were identified on Sheffield Children’s PACS database. Scans with syringes having an AP diameter of > 1 mm and extending over at least two vertebral bodies were reviewed. Patients with an identifiable [...]

March 2013 Publication year: 2013 Source:Journal of Clinical Neuroscience, Volume 20, Issue 3Fast-brain MRI is a promising technique for young children who require anesthesia for conventional MRI; however, poor contrast resolution and the use of one type of pulse sequence only has limitations. We aimed to review and document pitfalls of fast-brain MRI in non-sedated [...]

  http://lacpediatricneurosurgery.com/ CLICK HERE   PRE-MEETING – PEDIATRIC NEUROENDOSCOPY Date: March 4th (monday) – Hour: 7:00am – 5:00pm                   10th LATIN AMERICAN COURSE IN PEDIATRIC NEUROSURGERY Date: MONDAY , March 4th  4:00pm Registration open Meeting: TUESDAY, March 5th - FRIDAY, March 8th   Dear Colleagues and Friends, We would like to [...]

Glial tumours in children have distinct patterns of epigenetic alteration, chromosomal structure, and gene and protein expression that differentiate them from their histological counterparts in adults. Understanding paediatric gliomas at the molecular level provides important prognostic and therapeutic insights, such as which genetic alterations confer a favourable response to adjuvant therapy, or which signalling pathways [...]

Nat Rev Neurol. 2012 May 8;8(6):340-51. doi: 10.1038/nrneurol.2012.78. The clinical implications of medulloblastoma subgroups. (CLICK HERE) Northcott PA, Korshunov A, Pfister SM, Taylor MD. Source Division Molecular Genetics, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany. Abstract Medulloblastoma, the most common malignant paediatric brain tumour, is currently diagnosed and stratified using a combination of clinical [...]

Pediatr Blood Cancer. 2010 Mar;54(3):377-83. Primary chemotherapy for intracranial germ cell tumors: results of the third international CNS germ cell tumor study. CLICK HERE da Silva NS, Cappellano AM, Diez B, Cavalheiro S, Gardner S, Wisoff J, Kellie S, Parker R, Garvin J, Finlay J. Source Department of Pediatric Oncology, IOP-GRAACC/UNIFESP, São Paulo, SP, Brazil. [...]

World J Pediatr. 2010 May;6(2):103-10. Epub 2010 May 21. Management of subependymal giant cell tumors in tuberous sclerosis complex: the neurosurgeon’s perspective. Berhouma M. Source Department of Neurosurgery B (Unit 501), Pierre Wertheimer Hospital, Lyon, France. berhouma.moncef@yahoo.fr Abstract BACKGROUND: Tuberous sclerosis complex (TSC), an autosomal dominant genetic disorder, can lead to the development of hamartomas [...]