Category: Neurology


Adriane Gröger1, Benjamin Bender2, Isabel Wurster1, Grzegorz Lukasz Chadzynski2, Uwe Klose2, Daniela Berg1 Objectives Degeneration of dopaminergic neurons in the substantia nigra (SN) pars compacta is the primary cause of idiopathic Parkinson’s disease (iPD). In early stages of disease in particular, presentation of symptoms is non-specific leading to difficulties in differentiating between iPD and atypical [...]

  BMC Cancer. 2012 Dec 6;12:581. doi: 10.1186/1471-2407-12-581.   Neurofeedback to improve neurocognitive functioning of children treated for a brain tumor: design of a randomized controlled double-blind trial. ( CLICK HERE) de Ruiter MA, Schouten-Van Meeteren AY, van Mourik R, Janssen TW, Greidanus JE, Oosterlaan J, Grootenhuis MA. Source Psychosocial Department, Emma Children’s Hospital AMC, [...]

Headache Headache. 2006;46(5):726-731. The Impact of Intensive Patient Education on Clinical Outcome in a Clinic-Based Migraine Population (CLICK HERE) John Farr Rothrock, MD, Victoria A. Parada, MD, Cheryl Sims, Kristin Key, Naomi S. Walters, Richard M. Zweifler, Abstract Objective: To determine whether the addition of patient education to routine medical management improves the clinical status [...]

Pain, Heat, and Emotion with Functional MRI CLICK HERE Assia Jaillard, M.D., Ph.D., and Allan H. Ropper, M.D. N Engl J Med 2013; 368:1447-1449April 11, 2013DOI: 10.1056/NEJMe1213074 Share: This article has no abstract; the first 100 words appear below. Pain, in its various manifestations, is our most distressing human experience. A large volume of evidence [...]

Neuroenhancement of the Aging Brain: Restoring Skill Acquisition in Old Subjects CLICK HERE ORIGINAL ARTICLE Neuroenhancement of the Aging Brain:Restoring Skill Acquisition in Old Subjects Maximo Zimerman, MD, Marie Nitsch, MD, Pascal Giraux, MD, Christian Gerloff, MD, Leonardo G. Cohen, MD, and Friedhelm C. Hummel, MD Objective: Decline in cognitive functions, including impaired acquisition of [...]

Tremor in primary adult-onset dystonia: prevalence and associated clinical features ObjectiveTo investigate the frequency and the main clinical features of tremor in primary adult-onset dystonia (PAOD). MethodsThis cross-sectional study was conducted on 429 patients with PAOD from eight Italian movement disorder centres. ResultsOf the 429 dystonic patients, 72 (16.7%) had tremor. Although sex and age [...]

Randomized controlled trial of trigeminal nerve stimulation for drug-resistant epilepsy Objective:To explore the safety and efficacy of external trigeminal nerve stimulation (eTNS) in patients with drug-resistant epilepsy (DRE) using a double-blind randomized controlled trial design, and to test the suitability of treatment and control parameters in preparation for a phase III multicenter clinical trial.Methods:This is [...]

Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthca Background and Purpose—The authors present an overview of the current evidence and management recommendations for evaluation and treatment of adults with acute ischemic stroke. The intended audiences are prehospital care providers, physicians, allied health professionals, and hospital administrators responsible for [...]

Estimating and communicating prognosis in advanced neurologic disease Prognosis can no longer be relegated behind diagnosis and therapy in high-quality neurologic care. High-stakes decisions that patients (or their surrogates) make often rest upon perceptions and beliefs about prognosis, many of which are poorly informed. The new science of prognostication—the estimating and communication “what to expect”—is [...]

Whole-brain magnetic resonance spectroscopic imaging measures are related to disability in ALS Objective:To demonstrate the sensitivity of a recently developed whole-brain magnetic resonance spectroscopic imaging (MRSI) sequence to cerebral pathology and disability in amyotrophic lateral sclerosis (ALS), and compare with measures derived from diffusion tensor imaging. Methods:Whole-brain MRSI and diffusion tensor imaging were undertaken in [...]

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