Category: Functional


JAMA Neurol. 2013 Feb;70(2):163-71. doi: 10.1001/2013.jamaneurol.45. History, applications, and mechanisms of deep brain stimulation. Miocinovic S, Somayajula S, Chitnis S, Vitek JL. Source Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX, USA. Abstract Deep brain stimulation (DBS) is an effective surgical treatment for medication-refractory hypokinetic and hyperkinetic movement disorders, and [...]

Oncology Scan—Improvements in Dose Calculation, Deformable Registration, and MR-Guided Radiation Del The Physics Editorial Team for the International Journal of Radiation Oncology Biology Physics (IJROBP) includes 7 associate editors and 1 senior editor. It comprises physicists having diverse expertise from North America and Europe, and from small and large academic centers . The Physics Team [...]

Amygdalohippocampotomy: surgical technique and clinical results Clinical article Antonio Gonçalves-Ferreira, M.D., Ph.D.1, Alexandre Rainha Campos, M.D.1, Manuel Herculano-Carvalho, M.D.1, Jose Pimentel, M.D., Ph.D.2, Carla Bentes, M.D.3, Ana Rita Peralta, M.D.3, Carlos Morgado, M.D.4, and The Epilepsy Surgery Group Abstract Object The removal of mesial temporal structures, namely amygdalohippocampectomy, is the most efficient surgical procedure for [...]

Patients With Refractory Epilepsy Treated Using a Modified Multiple Subpial Transection Technique BACKGROUND: Multiple subpial transection (MST) is a potential surgical treatment for patients with epileptogenic foci located in cortical areas with higher functions. As neurosurgical teams have become more experienced with MST, the original technique has adapted. OBJECTIVE: To report our 6-year experience with [...]

World Neurosurg. 2012 Jun 19. pii: S1878-8750(12)00648-1. doi: 10.1016/j.wneu.2012.06.028. [Epub ahead of print] Deep Brain Stimulation for the Treatment of Alzheimer Disease and Dementias. Laxton AW, Lozano AM. Source Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada. Abstract OBJECTIVE: To review the use of deep brain stimulation (DBS) for treatment of [...]

Ann Neurol. 2010 Oct;68(4):521-34. doi: 10.1002/ana.22089. A phase I trial of deep brain stimulation of memory circuits in Alzheimer’s disease. Laxton AW, Tang-Wai DF, McAndrews MP, Zumsteg D, Wennberg R, Keren R, Wherrett J, Naglie G, Hamani C, Smith GS, Lozano AM. Source Division of Neurosurgery, University of Toronto, Toronto, Ontario, Canada. Abstract OBJECTIVE: Alzheimer [...]

Psychosurgery was developed early in human prehistory (trephination) as a need perhaps to alter aberrant behavior and treat mental illness. The “American Crowbar Case” provided an impetus to study the brain and human behavior. The frontal lobe syndrome was avidly studied. Frontal lobotomy was developed in the 1930s for the treatment of mental illness and [...]

Front Integr Neurosci. 2011;5:42. doi: 10.3389/fnint.2011.00042. Epub 2011 Aug 18.   Origin and evolution of deep brain stimulation. CLICK   http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157831/ CLICK Sironi VA. Source Research Institute on the History of Biomedical Thought, University of Milano Bicocca Milan, Italy. Abstract This paper briefly describes how the electrical stimulation, used since antiquity to modulate the nervous [...]

JAMA Neurol. 2013 Feb;70(2):163-71. doi: 10.1001/2013.jamaneurol.45. History, applications, and mechanisms of deep brain stimulation. http://archneur.jamanetwork.com/article.aspx?articleid=1391074 (CLICK HERE)   Miocinovic S, Somayajula S, Chitnis S, Vitek JL. Source Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX, USA. Abstract Deep brain stimulation (DBS) is an effective surgical treatment for medication-refractory hypokinetic and [...]

J Neurosurg. 2013 Mar 26. [Epub ahead of print] Radiosurgery for patients with unruptured intracranial arteriovenous malformations. http://www.ncbi.nlm.nih.gov/pubmed/23530863 (CLICK HERE) Ding D, Yen CP, Xu Z, Starke RM, Sheehan JP. Source Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia. Abstract Object The appropriate management of unruptured intracranial arteriovenous malformations (AVMs) remains controversial. [...]

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