Long term outcome of surgical treatment of Chiari Malformation without syringomyelia.Giammattei L, et al. J Neurosurg Sci. 2017.
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BACKGROUND: Surgical treatment for CM without syringomyelia is still under debate. The aim of this study was to evaluate the long term outcome of surgically treated patients for CM-I without syringomyelia.
METHODS: We selected all adult patients who underwent surgery for CM-I without syringomyelia between 1993 and 2010. Only patients with long term follow-up (>5 years) were included. Clinical manifestations, radiologic features, and follow-up data were analyzed. Patient’s outcome was assessed using the Chicago Chiari Outcome Scale (CCOS). Patient’s outcome was classified also as: “improved”, “unchanged”or “worse”.
RESULTS: Among 38 patients, 27 were females and 11 were males. Age ranged from 18 to 65 years (mean age 41 years). The average follow-up duration was 75 months (range 60-168 months). The most frequent symptoms of presentation were: headache (60%), neck pain (52.6%), postural or gait instability (47.3 %), upper limb paresthesias (44.7%). The most frequent signs of presentation were: nystagmus (44.7%), pyramidal signs (31.5 %), gait/balance impairment (23.6 %). Surgical treatment resulted in a long term success rate of 84.2% (32 patients improved at last follow-up). 31 patients (81.5%) achieved a CCOS score between 13 and 16. Headache improved in 86.9 % of patients, gait impairment in 83.3 %, paresthesias in 70% and neck pain in 65.2 %. Two patients (5.2%) were unchanged after surgery, four patients (10.5%) showed recurrence of their symptoms. There was no mortality.
CONCLUSIONS: Surgery is a safe and long term effective treatment for patients with CM-I without syringomyelia in the majority of patients.
PMID 28677937 [PubMed – as supplied by publisher]