Decompressive craniectomy in hemorrhagic cerebral venous thrombosis: clinicoradiological features and risk factors.

J Neurosurg. 2016 Oct 21:1-7. [Epub ahead of print]

Decompressive craniectomy in hemorrhagic cerebral venous thrombosis: clinicoradiological features and risk factors.

Abstract

OBJECTIVE Decompressive craniectomy (DC) is a life-saving treatment for severe hemorrhagic cerebral venous thrombosis (CVT). However, the correlations between the clinicoradiological features and surgical outcomes of this disease are not well established. Therefore, the authors endeavored to analyze the potential risk factors for this more severe subtype of CVT and to provide more evidence regarding the benefits of DC in patients with hemorrhagic CVT. METHODS The clinical features, radiological findings, and surgical outcomes of patients with severe hemorrhagic CVT who had undergone DC treatment in the period from January 2005 to March 2015 were retrospectively analyzed, and the risk factors for this disease were evaluated. RESULTS Fifty-eight patients, 39 females (67.2%) and 19 males (32.8%), with a mean age of 39.7 ± 12.5 years, were included in this study. The mean duration from symptom onset to surgery was 3.3 ± 1.9 days, and 21 patients experienced acute courses. On neuroimaging, the mean mass lesion volume was 114.7 ± 17.7 ml. Nine patients had bilateral lesions, and 7 patients had deep CVT. According to their hemorrhagic proportion, cases were divided into hemorrhage-dominated (27 [46.6%]) and edema-dominated (31 [53.4%]) groups. After 6 months of follow-up, 56.9% of patients had achieved a favorable outcome, and 8 patients had died. The hemorrhage-dominated lesions (p = 0.026) and deep cerebral venous involvement (p = 0.026) were significantly associated with a poor outcome. CONCLUSIONS In patients suffering from severe hemorrhagic CVT, DC is an effective life-saving treatment that is associated with favorable outcomes. Hemorrhage-dominated lesions and deep cerebral venous involvement have a significant impact on the outcome of this disease.

KEYWORDS:

CPP = cerebral perfusion pressure; CVT = cerebral venous thrombosis; DC = decompressive craniectomy; GCS = Glasgow Coma Scale; H/L = hemorrhage/lesion volume; ICP = intracranial pressure; cerebral venous thrombosis; decompressive surgery; intracerebral hemorrhage; mRS = modified Rankin Scale; vascular disorders

PMID:
27767398
DOI:
10.3171/2016.8.JNS161112


Categories: Vascular

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